Structure of PDB 7wnv Chain C

Receptor sequence
>7wnvC (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGKD
HIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGME
HLYSMKCVPLSDLLLEMLD
3D structure
PDB7wnv Structure of the ligand binding domain of estrogen receptor alpha in complex with covalent inhibitor CO9
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2I9 C M343 L346 T347 A350 E353 W383 L387 I424 H524 L525 Y526 C530 M34 L37 T38 A41 E44 W74 L78 I115 H201 L202 Y203 C207
External links
PDB RCSB:7wnv, PDBe:7wnv, PDBj:7wnv
PDBsum7wnv
PubMed37871388
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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