Structure of PDB 7w3u Chain C

Receptor sequence
>7w3uC (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]
RFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQ
KMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIE
EMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNI
YESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRY
TFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLSYEYDLIGVTVHTGTADG
GHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMFEKT
HSAYMLFYKRMEEYKFDVSSELLEWIWHDNMQF
3D structure
PDB7w3u Structural Insights into the Catalytic Mechanism and Ubiquitin Recognition of USP34.
ChainC
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C C2018 H2020 C2065 C127 H129 C174
BS02 AYE C A1901 C1903 Q1976 G2163 A10 C12 Q85 G251
Gene Ontology
Molecular Function
GO:0004843 cysteine-type deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:7w3u, PDBe:7w3u, PDBj:7w3u
PDBsum7w3u
PubMed35588869
UniProtQ70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 (Gene Name=USP34)

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