Structure of PDB 7w0t Chain C

Receptor sequence
>7w0tC (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
VELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG
FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQ
YWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQ
ERVFPLFSVCSTGTYLRIWP
3D structure
PDB7w0t A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
ChainC
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C T382 N383 T384 R385 A410 L423 F426 Q436 S499 C501 S502 T41 N42 T43 R44 A69 L82 F85 Q95 S158 C160 S161
External links
PDB RCSB:7w0t, PDBe:7w0t, PDBj:7w0t
PDBsum7w0t
PubMed35982226
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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