Structure of PDB 7vza Chain C

Receptor sequence
>7vzaC (length=355) Species: 1946 (Streptomyces kasugaensis) [Search protein sequence]
HMALRVGIVYGTRPEAIKLAPLVLALDADPGFEPVIITTGLDEINELFGL
RPRHNLDIMRQRLSAMASRIVGELGDPLLDELVDVAVVQGDTSTAFAAAY
AAACERIPVAHLEAGLRTGDRFEPFPEEINRRLITQLADLHFAPTADAAG
NLLAEGVRSDDVYVTGNTVIDAMHLVLELDAFTEGRQTVLLTMHRRESWG
IPMGRVAAAVAELCRSRPTLRFVIPLHPNPEVRRVFRSHLSSLTQVLLCE
PLRYSEFIRLMHRAVLVLTDSGGVQEEAPTLGKPVLVLRDRTERPEGIAA
GCARLVGTDPALIVKEVGRLLDDPEAYEAMRRCYGEGDAAARCLEALRER
WLSSP
3D structure
PDB7vza KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity.
ChainC
Resolution2.58 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 5.1.3.14: UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP C R12 P13 H209 L267 Y269 F272 S286 G287 E292 R13 P14 H194 L252 Y254 F257 S271 G272 E277
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity
GO:0016853 isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:7vza, PDBe:7vza, PDBj:7vza
PDBsum7vza
PubMed35203422
UniProtA0A0K1H2R6

[Back to BioLiP]