Structure of PDB 7uzg Chain C

Receptor sequence
>7uzgC (length=602) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATI
QVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQ
SIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKH
KIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEGVKEKLSMVQVWPVRQV
RPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLS
KYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVAN
TSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGR
LAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPG
GDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY
YDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKL
IKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNK
ITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRS
LE
3D structure
PDB7uzg Structure of V-ATPase with NCOA7B
ChainC
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C G253 G255 K256 T257 V258 R280 F445 Y525 G239 G241 K242 T243 V244 R266 F431 Y511
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0015986 proton motive force-driven ATP synthesis
GO:0036295 cellular response to increased oxygen levels
GO:0046034 ATP metabolic process
GO:0097401 synaptic vesicle lumen acidification
GO:1902600 proton transmembrane transport
Cellular Component
GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0030133 transport vesicle
GO:0030141 secretory granule
GO:0030665 clathrin-coated vesicle membrane
GO:0033176 proton-transporting V-type ATPase complex
GO:0033180 proton-transporting V-type ATPase, V1 domain
GO:0043231 intracellular membrane-bounded organelle
GO:0098850 extrinsic component of synaptic vesicle membrane
GO:1904949 ATPase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7uzg, PDBe:7uzg, PDBj:7uzg
PDBsum7uzg
PubMed
UniProtD4A133

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