Structure of PDB 7tu5 Chain C

Receptor sequence
>7tu5C (length=429) Species: 398720 (Leeuwenhoekiella blandensis MED217) [Search protein sequence]
NWEHLLSLKRQGDTAKRLRIELGFEVDYDRIIFSAPFRSLQDKTQVIPFV
HTRLTHSLEVSVVGRSLGRMVGKKLLEKYPHLEQVYGYKFNDFGAIVAAA
ALAHDIGNPPFGHSGEKAIGEFFKNGYGKRYKDSLTAKEYQDLIKFEGNA
NGFKVLSQSKPGAQGGLRLSYATLGAFMKYPKESLPHKPSDHIADKKYGF
FQSERALFEDVAQELGLLKRSTTDDVSWSRHPLAYLVEAADDICYTIIDF
EDGINLGLIPEEYALEYMVKLVGQTIDRNKYNALQETSDRVSYLRALAIG
TLINESVDTFMKYEEEILAGTFDQSLIDKSNYQAQITDIINLSIERIYNS
REVIEKEIAGYEILSTLLEARCRALDNNDTHYNQLIQQLLAPNDHSEKSL
YENLIQICAEVSTMTDGKALRNYKKIKGL
3D structure
PDB7tu5 High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.5.1: dGTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C H68 H116 D253 H56 H104 D241
Gene Ontology
Molecular Function
GO:0008832 dGTPase activity
GO:0016787 hydrolase activity
GO:0016793 triphosphoric monoester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006203 dGTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7tu5, PDBe:7tu5, PDBj:7tu5
PDBsum7tu5
PubMed35643313
UniProtA3XHN1

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