Structure of PDB 7tjh Chain C

Receptor sequence
>7tjhC (length=546) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ADAQRSHYTVYPSLPHIPFVKLLSGKESEVNVEKRWELYHQLHSHFHDQV
DHIIDNIEADLKAEISDLLYSRCFNTIFLLGSDSTTKIELKDESSRYNVL
IELTPKESPNVRMMLRRSMYKLYSAADAEENDVSYDLSLVENFKRLFGKD
LAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISLIFNINTNLSNIE
KNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSDRF
VEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVNVDFLND
DYLKILSRCPTFMFFVEGLIKQNRGLEEFFVEFLVRENPINGHAKFVARF
LEEELNITNFNLIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIF
QELFTLDNRSGLLTQSIFPSYKSNIEDNLLSWEQVLPSLSGDLDKIMAPV
LGQLFKLYREANMTINIYDFYIAFRETLPKEEILNFIRKDPSNTKLLELA
ETPDAFDKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI
3D structure
PDB7tjh A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K134 P137 R140 M141 R144 R145 K106 P109 R112 M113 R116 R117
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006270 DNA replication initiation
GO:0030466 silent mating-type cassette heterochromatin formation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tjh, PDBe:7tjh, PDBj:7tjh
PDBsum7tjh
PubMed35217664
UniProtP54790|ORC3_YEAST Origin recognition complex subunit 3 (Gene Name=ORC3)

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