Structure of PDB 7tj6 Chain C

Receptor sequence
>7tj6C (length=391) Species: 869211 (Spirochaeta thermophila DSM 6578) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQRSATRILS
YRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLSAFYWT
ITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLVSKLDA
AKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEEREVLK
ELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEY
IIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALILRAPR
TATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVRR
3D structure
PDB7tj6 Anionic lipids unlock the gates of select ion channels in the pacemaker family.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 D21 C P194 L205 P167 L178
BS02 CMP C F366 G367 T378 R418 F339 G340 T351 R391
BS03 D21 C L109 S157 L82 S130
BS04 D21 C Y170 L171 Y143 L144
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tj6, PDBe:7tj6, PDBj:7tj6
PDBsum7tj6
PubMed36352139
UniProtG0GA88

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