Structure of PDB 7ssj Chain C

Receptor sequence
>7ssjC (length=216) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
IIKLRKEIERLEEKLEDANERIAELVKLEERQRIARDLHDTLGQKLSLIG
LKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDE
LINIKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQ
AKTCRVDIQQLWKEVVITVSDDGTFKGFSKGHGLLGMRERLEFANGSLHI
DTENGTKLTMAIPNNS
3D structure
PDB7ssj An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
ChainC
Resolution2.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP C E289 N293 H297 S298 F324 K325 H335 G336 L337 E140 N144 H148 S149 F175 K176 H182 G183 L184
BS02 MG C E289 N293 E140 N144
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ssj, PDBe:7ssj, PDBj:7ssj
PDBsum7ssj
PubMed36693130
UniProtO34757|DESK_BACSU Sensor histidine kinase DesK (Gene Name=desK)

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