Structure of PDB 7sne Chain C

Receptor sequence
>7sneC (length=180) Species: 520 (Bordetella pertussis) [Search protein sequence]
GDPPATVYRYDSRPPEDVFQNGFTAWGNNDNVLEHLTGRSSQVGSSNSAF
VSTSSSRRYTEVYLEHRMQEAVEAERAGRGTGHFIGYIYEVRADNNFYGA
ASSYFEYVDTYGDNAGRILAGALATYQSEYLAHRRIPPENIRRVTRVYHN
GITGETTTTEYSNARYVSQQTRANPNPYTS
3D structure
PDB7sne Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
ChainC
Resolution1.00011 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9XR C R9 Y10 D11 S12 R13 W26 H35 L36 G38 S41 Q42 S52 T53 Y59 Y63 E129 R9 Y10 D11 S12 R13 W26 H35 L36 G38 S41 Q42 S52 T53 Y59 Y63 E129
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7sne, PDBe:7sne, PDBj:7sne
PDBsum7sne
PubMed35378130
UniProtP04977|TOX1_BORPE Pertussis toxin subunit 1 (Gene Name=ptxA)

[Back to BioLiP]