Structure of PDB 7ryr Chain C

Receptor sequence
>7ryrC (length=389) Species: 154 (Spirochaeta thermophila) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQASATRIIN
PALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLSAFYWTITTL
TTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLVSKLDAAKLL
HRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEEREVLKELPH
PLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRA
GEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALILRAPRTATV
RARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVRRKE
3D structure
PDB7ryr Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
ChainC
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP C Y357 F366 G367 E368 M369 A370 R418 Y326 F335 G336 E337 M338 A339 R387
BS02 PGW C L32 H149 A166 Y170 L23 H118 A135 Y139
BS03 PGW C T195 Y199 V202 L206 T164 Y168 V171 L175
BS04 PGW C P194 V198 P163 V167
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:7ryr, PDBe:7ryr, PDBj:7ryr
PDBsum7ryr
PubMed36376326
UniProtG0GA88

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