Structure of PDB 7rue Chain C

Receptor sequence
>7rueC (length=340) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIHKILKGNDDRLLV
VIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTVGWKG
LINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADL
MSWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAP
HCFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKA
GLPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLV
EGNQSLEPLAYGKSITDACIGWEDTDALLRQLANAVKARR
3D structure
PDB7rue An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7QH C R92 A164 R165 K186 R234 H268 R86 A158 R159 K180 R228 H262
BS02 MN C C61 H268 E302 D326 C55 H262 E296 D317
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rue, PDBe:7rue, PDBj:7rue
PDBsum7rue
PubMed34761906
UniProtP0AB91|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)

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