Structure of PDB 7rsi Chain C

Receptor sequence
>7rsiC (length=294) Species: 9606 (Homo sapiens) [Search protein sequence]
MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDKDLKFVFDAVFDETST
QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMYL
TMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQK
GVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHATSSRSHAVFQIYLRQQD
KTASINQNVRIAKMSLIDLAGSERFVEGTNINRSLLALGNVINALADSKR
SKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAK
3D structure
PDB7rsi Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.
ChainC
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C R17 R19 P20 T115 G116 A117 G118 T120 H121 R6 R8 P9 T80 G81 A82 G83 T85 H86
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7rsi, PDBe:7rsi, PDBj:7rsi
PDBsum7rsi
PubMed34797717
UniProtQ8NI77|KI18A_HUMAN Kinesin-like protein KIF18A (Gene Name=KIF18A)

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