Structure of PDB 7rs3 Chain C

Receptor sequence
>7rs3C (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPIYSSMMGLLTNLADRELVHMINWAKRVPG
FVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGV
EIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKSLEEKDHIHR
VLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
3D structure
PDB7rs3 Dual-mechanism estrogen receptor inhibitors.
ChainC
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR C M522 L525 M195 L198
BS02 7OR C T347 A350 D351 E353 L387 L391 G521 H524 L525 T31 A34 D35 E37 L71 L75 G194 H197 L198
External links
PDB RCSB:7rs3, PDBe:7rs3, PDBj:7rs3
PDBsum7rs3
PubMed34452998
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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