Structure of PDB 7qqh Chain C

Receptor sequence
>7qqhC (length=617) Species: 9606 (Homo sapiens) [Search protein sequence]
RAELLDLKAGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCSLTA
DGLPLHFFIQTVRPKDTVMCYRVRWEEGRAVEHAMFLGDAAAHWYGGAEM
RTQHWPIRLDGQQEPQPFVTSDVYSSDAAFGGILERYWLSSRAAAIKVND
SVPFHLGWNSTERSLRLQARYHDTPYKPPAPELSYRVCVGSDVTSIHKYM
VRRYFNKPSRVPAPEAFRDPIWSTWALYGRAVDQDKVLRFAQQIRLHHFN
SSHLEIDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVN
YNSSRFGEGVERELFVREPTGRLPALVRWWNGIGAVLDFTHPKARDWFQG
HLRRLRSRYSVASFKFDAGEVSYLPRDFSTYRPLPDPSVWSRRYTEMALP
FFSLAEVRVGYQSQNISCFFRLVNRDSVWGYDLGLRSLIPAVLTVSMLGY
PFILPDMVGGNAVPQRTAGGDVPERELYIRWLEVAAFMPAMQFSIPPWRY
DAEVVAIAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDET
AHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFDKTPVL
LTDYPVDLDEIAYFTWA
3D structure
PDB7qqh The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.
ChainC
Resolution2.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC C D213 Y215 W321 W426 R504 N520 D122 Y124 W225 W330 R408 N424
BS02 GLA C W321 D353 D354 W390 W426 K461 D463 R504 R517 N520 W225 D257 D258 W294 W330 K365 D367 R408 R421 N424
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qqh, PDBe:7qqh, PDBj:7qqh
PDBsum7qqh
PubMed36129849
UniProtQ6NSJ0|MYORG_HUMAN Myogenesis-regulating glycosidase (Gene Name=MYORG)

[Back to BioLiP]