Structure of PDB 7q3o Chain C
Receptor sequence
>7q3oC (length=63) Species:
9606
(Homo sapiens) [
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TRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKI
WFQNRRAKERKVN
3D structure
PDB
7q3o
Structure of CDX1 bound to hydroxymethylated DNA
Chain
C
Resolution
2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
dna
C
T183 R184 T185 R190 V191 Y193 R198 R228 Q229 I232 N236 K240
T1 R2 T3 R8 V9 Y11 R16 R46 Q47 I50 N54 K58
BS02
dna
C
Y189 R190 V192 I213 K216 Q235 R238 R242
Y7 R8 V10 I31 K34 Q53 R56 R60
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:7q3o
,
PDBe:7q3o
,
PDBj:7q3o
PDBsum
7q3o
PubMed
UniProt
P47902
|CDX1_HUMAN Homeobox protein CDX-1 (Gene Name=CDX1)
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