Structure of PDB 7pr3 Chain C

Receptor sequence

>7pr3C (length=107) Species: 559292 (Saccharomyces cerevisiae S288C)

EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGY
SYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLIT
YLKKATE

3D structure

• PDB: 7pr3 Protein Frameworks with Thiacalixarene and Zinc.
• Chain: C
• Resolution: 2.37 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	80M	C	E66 T69 N70 K73 Y74 K86	E70 T73 N74 K77 Y78 K90
BS02	80M	C	H39 N56 V57 L58	H43 N60 V61 L62
BS03	HEC	C	R13 C14 C17 H18 G29 P30 L32 I35 G41 Y46 Y48 T49 N52 W59 M64 L68 T78 K79 M80 A81 F82	R17 C18 C21 H22 G33 P34 L36 I39 G45 Y50 Y52 T53 N56 W63 M68 L72 T82 K83 M84 A85 F86
BS04	80M	C	S2 A3 K4	S6 A7 K8
BS05	ZN	C	H33 E103	H37 E107
BS06	ZN	C	E-3 E88	E1 E92

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:7pr3, PDBe:7pr3, PDBj:7pr3
• PDBsum: 7pr3
• PubMed: 35529063
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)