Structure of PDB 7ovs Chain C

Receptor sequence
>7ovsC (length=379) Species: 10090 (Mus musculus) [Search protein sequence]
PRIMRLVAECSRSGARAGELRLPHGTVATPVFMPVGTQATMKGITTEQLD
SLGCRICLGNTYHLGLRPGPELIRKAQGLHGFMNWPHNLLTDSGGFLSEV
TEEGVHFRSPYDGEETLLSPERSVEIQNALGSDIIMQLDHVVSTGPLVEE
AMHRSVRWLDRCIAAHKHPDKQNLFAIIQGGLNADLRTTCLKEMTKRDVP
GFAIGGLSGGESKAQFWKMVALSTSMLPKDKPRYLMGVGYATDLVVCVAL
GCDMFDCVYPTRTARFGSALVPTGNLQLKKKQYAKDFSPINPECPCPTCQ
THSRAFLHALLHSDNTTALHHLTVHNIAYQLQLLSAVRSSILEQRFPDFV
RNFMRTMYGDHSLCPAWAVEALASVGIML
3D structure
PDB7ovs Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase.
ChainC
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.64: tRNA-guanosine(34) queuine transglycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C C317 C319 C322 H348 C294 C296 C299 H325
BS02 2I2 C K236 A389 W390 K213 A366 W367
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0032473 cytoplasmic side of mitochondrial outer membrane
GO:0032991 protein-containing complex
GO:0120507 tRNA-guanine transglycosylase complex
GO:1990234 transferase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ovs, PDBe:7ovs, PDBj:7ovs
PDBsum7ovs
PubMed35815944
UniProtQ9JMA2|TGT_MOUSE Queuine tRNA-ribosyltransferase catalytic subunit 1 (Gene Name=Qtrt1)

[Back to BioLiP]