Structure of PDB 7oue Chain C

Receptor sequence
>7oueC (length=242) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence]
GSHMIARIIGEIGIEGARFIEENIDEQFKALRYLSKGIDSETFVKLVIAN
SLVSYQLTGKGEQWWWEFAKYFYGRDVKSIYLAYKEFLPNSRFNRRLIPQ
KLSRIRRVETFLSTLTEERIEEYYGDMSSLWGSIARALGVDKESKTVVFS
VKMFGYAARIVLSTFNPYPMEIPIPEDSRIVKLTKKLTNEKPRKFWMKIA
RESGVPPLHIDSILWPLLGGASIDSAPPELRDKLAELIKIIR
3D structure
PDB7oue Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
ChainC
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C Y52 Q53 L54 T55 G56 R93 Q97 R101 V137 K142 T143 D174 R176 Y55 Q56 L57 T58 G59 R96 Q100 R104 V140 K145 T146 D177 R179
Gene Ontology
Molecular Function
GO:0000702 oxidized base lesion DNA N-glycosylase activity
GO:0003824 catalytic activity
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0016829 lyase activity
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7oue, PDBe:7oue, PDBj:7oue
PDBsum7oue
PubMed36300625
UniProtQ9UZY0|AGOG_PYRAB N-glycosylase/DNA lyase (Gene Name=PYRAB10170)

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