Structure of PDB 7opo Chain C

Receptor sequence
>7opoC (length=295) Species: 9606 (Homo sapiens) [Search protein sequence]
SIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQ
LYAMKVLKKATLKVRDRDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG
GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLD
EEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWW
SFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRML
FKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPA
3D structure
PDB7opo A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host.
ChainC
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP C G77 S78 F79 V82 A98 K100 D148 L150 K195 E197 N198 L200 T210 K216 G32 S33 F34 V37 A53 K55 D96 L98 K143 E145 N146 L148 T158 K164
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7opo, PDBe:7opo, PDBj:7opo
PDBsum7opo
PubMed35078976
UniProtP51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 (Gene Name=RPS6KA3)

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