Structure of PDB 7opi Chain C

Receptor sequence
>7opiC (length=842) Species: 9606 (Homo sapiens) [Search protein sequence]
NLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMR
KAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYK
LDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMIST
MRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARH
TGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAAL
AEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYA
NYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILP
PFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAE
QYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLN
GFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVM
KTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPP
IKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFEL
LELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCT
TVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMG
KDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLL
NYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVR
DVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL
3D structure
PDB7opi Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
ChainC
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 07I C L1066 K1067 R1074 Q1107 V1110 L604 K605 R612 Q645 V648
Gene Ontology
Biological Process
GO:0000245 spliceosomal complex assembly

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Molecular Function
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Biological Process
External links
PDB RCSB:7opi, PDBe:7opi, PDBj:7opi
PDBsum7opi
PubMed34301950
UniProtO75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Gene Name=SF3B1)

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