Structure of PDB 7om7 Chain C

Receptor sequence

>7om7C (length=632) Species: 83810 (Thosea asigna virus) [Search protein sequence]

TRLSLEAMLAERAMVARQDLAGLKRKLAGADRVLAPQSPEQCGRESAQAQ
ARSVTSELKSAVKEAQGLEHQTLDFLEQLGEYPVCGILHGDHPVHPSGTH
NNNGKVSVKRQFAAGSDALTCAFRFEDSDLVRETALKTTYTDGTWAGFVQ
RLKMQTTRKCVQEKVSRKLLKQLFPYDPQKLVDVSGELSELVLGIKTNAI
ASAGPPYWRTKRDALPDMLDCVLPLLYDHIVRKDLTTLRNKHPELFLAEC
KNKTDRYEVESLGEKTRPYFSHPFHLSALVSVLSQSFSGALKIMTEDSTS
FNAYGFSWTNGGAEDLAIWARQAGEAGKKPPRIACYGDDTDIYYRKDGKL
YRICPDFKQMDGSVDATTIEAVVDYVVDAHVKQYPTARQFWEEVGKLWVE
MATQSPFLIDGTKVYRKMQKDGLMTGVVGTTLFDTVKSALAYNDWADQLM
FGSLNLLEEKYAIEFFKNKHGLVIKEGTWKPALVNEDPGFGELWTEQKFL
GLQLKVVRRENEKVYVPNLPFEDWLTMWVTPRSRSKETETMRERTLFDRA
RGLLVTGAVFDERARGLMGAVINSTAPEVVCMRVISDGYPSYDWVVSLYS
RDHPCDMPRVFPEAATLIASYRKQVMDTRVVI

3D structure

PDB

7om7 Snapshots of a Non-Canonical RdRP in Action.

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	A214 S215 K224 K264 Y282 F283 S294 Q298 Y317 G318 S320 T322 G439 V441 W633	A201 S202 K211 K251 Y269 F270 S281 Q285 Y304 G305 S307 T309 G426 V428 W594
BS02	rna	C	R269 Y349 G350 D351 D352 L513 M540 R545 D563 R564 G567 L568 T571 V599	R256 Y336 G337 D338 D339 L500 M527 R532 D548 R549 G552 L553 T556 V584

External links

PDB	RCSB:7om7, PDBe:7om7, PDBj:7om7
PDBsum	7om7
PubMed	34203380
UniProt	Q6A562

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