Structure of PDB 7oal Chain C

Receptor sequence
>7oalC (length=298) Species: 9606 (Homo sapiens) [Search protein sequence]
VLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLS
TEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVK
RADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENS
APVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGC
GVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRR
MLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRK
3D structure
PDB7oal Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase.
ChainC
Resolution2.17 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D141 K143 C146 G162 T182
Catalytic site (residue number reindexed from 1) D136 K138 C141 G157 T177
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V62 C I18 A39 V75 F91 F93 M94 G96 C146 L148 G161 G162 I13 A34 V70 F86 F88 M89 G91 C141 L143 G156 G157
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7oal, PDBe:7oal, PDBj:7oal
PDBsum7oal
PubMed34543009
UniProtO14936|CSKP_HUMAN Peripheral plasma membrane protein CASK (Gene Name=CASK)

[Back to BioLiP]