Structure of PDB 7nyd Chain C

Receptor sequence
>7nydC (length=809) Species: 9606 (Homo sapiens) [Search protein sequence]
SSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGGQPCVGNAFETQS
CEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCEDS
ERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGD
GKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKR
RSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEP
FWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLK
QNDFNSVEEKKCKSSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGF
ISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCA
SVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGA
ACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRS
CVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQD
EGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLP
VLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMK
NARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERS
KRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDA
ESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTS
IRPCAAETQ
3D structure
PDB7nyd Structural basis of soluble membrane attack complex packaging for clearance.
ChainC
Resolution3.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA C L427 D428 D431 W484 L415 D416 D419 W472
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0031640 killing of cells of another organism
GO:0050778 positive regulation of immune response
Cellular Component
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0070062 extracellular exosome

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7nyd, PDBe:7nyd, PDBj:7nyd
PDBsum7nyd
PubMed34667172
UniProtP10643|CO7_HUMAN Complement component C7 (Gene Name=C7)

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