Structure of PDB 7njo Chain C

Receptor sequence
>7njoC (length=533) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
TISAADIEGAIEDYVSSFSADTEREEIGTVIDAGDGIAHVEGLPSVMTQE
LLEFPGGVLGVALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSVPVGD
AFLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQTGIK
AIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPKQQVRC
VYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGS
AIGQHWMYNGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYL
HSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITDGQCF
LESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELE
AFALDAASKAQLDRGARLVELLKQPQYSPLAVEEQVVAIFLGTQGHLDSV
PVEDVQRFESELLEHVKASHSDIFDGIRETKKLSEEAEEKLVSVINEFKK
GFQASDGSSVVVAEALDPEDLEKESVKVRKPAP
3D structure
PDB7njo Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
ChainC
Resolution2.92 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C R174 K175 G177 K178 T179 A180 F360 R365 Q435 R170 K171 G173 K174 T175 A176 F356 R361 Q426
BS02 ADP C V374 S375 R376 V370 S371 R372
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7njo, PDBe:7njo, PDBj:7njo
PDBsum7njo
PubMed34782468
UniProtA0R202|ATPA_MYCS2 ATP synthase subunit alpha (Gene Name=atpA)

[Back to BioLiP]