Structure of PDB 7njl Chain C

Receptor sequence
>7njlC (length=533) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
ISAADIEGAIEDYVSSFSADTEREEIGTVIDAGDGIAHVEGLPSVMTQEL
LEFPGGVLGVALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSVPVGDA
FLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQTGIKA
IDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPKQQVRCV
YVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGSA
IGQHWMYNGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLH
SRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITDGQCFL
ESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEA
FAALDAASKAQLDRGARLVELLKQPQYSPLAVEEQVVAIFLGTQGHLDSV
PVEDVQRFESELLEHVKASHSDIFDGIRETKKLSEEAEEKLVSVINEFKK
GFQASDGSSVVVAEALDPEDLEKESVKVRKPAP
3D structure
PDB7njl Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
ChainC
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C R174 K175 G177 K178 T179 A180 F360 Q435 R169 K170 G172 K173 T174 A175 F355 Q426
BS02 ADP C V374 R376 V369 R371
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7njl, PDBe:7njl, PDBj:7njl
PDBsum7njl
PubMed34782468
UniProtA0R202|ATPA_MYCS2 ATP synthase subunit alpha (Gene Name=atpA)

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