Structure of PDB 7n3y Chain C

Receptor sequence
>7n3yC (length=374) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQQL
KTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQ
VVKAEEGITGYLTIKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELDSE
GRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLDKI
GKKIVLMGNVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAIQF
IINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWN
MLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDLDI
LVPIPKFEARYKYNLRNHNVLEMF
3D structure
PDB7n3y Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
ChainC
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C L284 D286 L271 D273
BS02 dna C R205 R208 R273 R290 R192 R195 R260 R277
BS03 dna C M314 N317 M301 N304
BS04 dna C H32 Y33 Q34 N317 L318 L350 H22 Y23 Q24 N304 L305 L337
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7n3y, PDBe:7n3y, PDBj:7n3y
PDBsum7n3y
PubMed36198268
UniProtP38207|APN2_YEAST DNA-(apurinic or apyrimidinic site) endonuclease 2 (Gene Name=APN2)

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