Structure of PDB 7mza Chain C

Receptor sequence
>7mzaC (length=537) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGR
PGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALV
EVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAAS
SGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEK
NSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYC
LYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRG
IQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMV
FSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFS
TAVVTLIEDGKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLA
YVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKC
MRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTW
3D structure
PDB7mza Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
ChainC
Resolution3.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6EU C Y511 S512 L515 M547 T550 N551 E570 Y319 S320 L323 M355 T358 N359 E378 BindingDB: Ki=0.13nM,IC50=180nM
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mza, PDBe:7mza, PDBj:7mza
PDBsum7mza
PubMed34496225
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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