Structure of PDB 7mp3 Chain C

Receptor sequence
>7mp3C (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRQGFVLSLCHLQK
VKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHC
CT
3D structure
PDB7mp3 Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability.
ChainC
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C R438 R458 R462 R14 R34 R38
BS02 peptide C R438 K478 H479 Y480 L481 M495 D496 Q499 R14 K52 H53 Y54 L55 M69 D70 Q73
External links
PDB RCSB:7mp3, PDBe:7mp3, PDBj:7mp3
PDBsum7mp3
PubMed35625882
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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