Structure of PDB 7mj1 Chain C

Receptor sequence
>7mj1C (length=200) Species: 220668 (Lactiplantibacillus plantarum WCFS1) [Search protein sequence]
NGFPEVIYGAGKTATQIVGIVQALSQQTLPILTTRLSAEKFAALQPALPT
AVYHATAQCMTVGEPAPKTPGYIAVVTAGTSDQPVAEEAAVTAETFGNRV
ERVYDVGVAGIHRLFAKLDVIRGARVVIVIAGMEGALASVVGGLVDKPVI
AVPTSVGYGTSFQGMTALLTMLNSCASGITVVNIDNGFGAAYSASMVNQM
3D structure
PDB7mj1 The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
ChainC
Resolution3.402 Å
3D
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Enzymatic activity
Enzyme Commision number 2.5.1.143: pyridinium-3,5-biscarboxylic acid mononucleotide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C V191 S223 V145 S177
BS02 NAD C A124 T126 S127 D128 G153 V154 A177 G178 M179 E180 A182 L183 Y204 A78 T80 S81 D82 G107 V108 A131 G132 M133 E134 A136 L137 Y158
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7mj1, PDBe:7mj1, PDBj:7mj1
PDBsum7mj1
PubMed34548397
UniProtF9UST0|LARB_LACPL Pyridinium-3,5-biscarboxylic acid mononucleotide synthase (Gene Name=larB)

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