Structure of PDB 7mi9 Chain C

Receptor sequence
>7mi9C (length=339) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence]
RGLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLT
TAALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPET
CLNLARRWIVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMR
APSLEVLLGIEGASAGRYFQHFSRMLRGGDGEGMGFDFTTRNRRPPKDPV
NALLSFAYAMLTREWTVALAAVGLDPYRGFYHQPRFGRPALALDMMEPFR
PLIADSTVLMAINNGEIRTGDFVRSAGGCNLTDSARKRFIAGFERRMEQE
VTHPIFKYTISYRRLLEVQARLLTRYLSGEIPAYPNFVT
3D structure
PDB7mi9 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
ChainC
Resolution3.89 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K526 Y527 K307 Y308
BS02 dna C Y232 R234 K235 D236 G237 T269 R544 Y13 R15 K16 D17 G18 T50 R325
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7mi9, PDBe:7mi9, PDBj:7mi9
PDBsum7mi9
PubMed34588691
UniProtQ74H36|CS4F1_GEOSL CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion (Gene Name=cas4-cas1)

[Back to BioLiP]