Structure of PDB 7mi5 Chain C

Receptor sequence
>7mi5C (length=362) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence]
LPDEVRFLSHLSVEPRPIIPADGRGLPLYVQSPKAYVRKDGDCLVIEEER
VRVAEARLGETSQVALFGNATLTTAALHECLRREIPVTWLSYGGWFMGHT
VSTGHRNVETRTYQYQRSFDPETCLNLARRWIVAKIANCRTLLRRNWRGE
GDEAKAPPGLLMSLQDDMRHAMRAPSLEVLLGIEGASAGRYFQHFSRMLR
GGDGEGMGFDFTTRNRRPPKDPVNALLSFAYAMLTREWTVALAAVGLDPY
RGFYHQPRFGRPALALDMMEPFRPLIADSTVLMAINNGEIRTGDFVRSAG
GCNLTDSARKRFIAGFERRMEQEVTHPIFKYTISYRRLLEVQARLLTRYL
SGEIPAYPNFVT
3D structure
PDB7mi5 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
ChainC
Resolution3.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R234 K235 G237 R38 K39 G41
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7mi5, PDBe:7mi5, PDBj:7mi5
PDBsum7mi5
PubMed34588691
UniProtQ74H36|CS4F1_GEOSL CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion (Gene Name=cas4-cas1)

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