Structure of PDB 7m5c Chain C

Receptor sequence
>7m5cC (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEQVAQDTEEVFRSYVFYRHQQEQADPEMVTLPLQPSSTMGQVGRQLAI
IGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVA
LLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAA
L
3D structure
PDB7m5c Structural basis of BAK activation in mitochondrial apoptosis initiation.
ChainC
Resolution3.06 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C I85 Y89 E92 F93 M96 H99 I114 S117 L118 N124 G126 R127 F134 I55 Y59 E62 F63 M66 H69 I84 S87 L88 N94 G96 R97 F104
BS02 CU C H141 H145 H111 H115
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:7m5c, PDBe:7m5c, PDBj:7m5c
PDBsum7m5c
PubMed35017502
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

[Back to BioLiP]