Structure of PDB 7lw2 Chain C

Receptor sequence

>7lw2C (length=141) Species: 42789 (enterovirus D68)

GPGFGGVFVGSFKIINYHLATIEERQSAIYVDWQSDVLVTPIAAHGRHQI
ARCKCNTGVYYCRHRDKSYPVCFEGPGIQWIEQTEYYPARYQTNVLLAAG
PAEAGDCGGLLVCPHGVIGLLTAGGGGIVAFTDIRNLLWLD

3D structure

• PDB: 7lw2 Crystal structure of EV-D68 2A protease C107A mutant
• Chain: C
• Resolution: 2.57 Å

Enzymatic activity

• Enzyme Commision number: 2.7.7.48: RNA-directed RNA polymerase.
  3.4.22.28: picornain 3C.
  3.4.22.29: picornain 2A.
  3.6.1.15: nucleoside-triphosphate phosphatase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	C	C53 C55 C113 H115	C53 C55 C113 H115

Gene Ontology

Molecular Function

• GO:0008233 peptidase activity

Biological Process

• GO:0006508 proteolysis
• GO:0016032 viral process

External links

• PDB: RCSB:7lw2, PDBe:7lw2, PDBj:7lw2
• PDBsum: 7lw2
• UniProt: A0A097BW19