Structure of PDB 7lmm Chain C

Receptor sequence
>7lmmC (length=157) Species: 9913 (Bos taurus) [Search protein sequence]
KNRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYLA
RVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSY
IHSKVQVIYKAPSGAGSATYFYQLWYDQDYARFESPPKTQPTEDNKYKFC
ASCARLA
3D structure
PDB7lmm DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
ChainC
Resolution2.798 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C I763 P764 D765 Y772 W793 E818 D819 Y824 I39 P40 D41 Y48 W69 E94 D95 Y100
BS02 ZN C H790 C817 H66 C93
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:7lmm, PDBe:7lmm, PDBj:7lmm
PDBsum7lmm
PubMed33941775
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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