Structure of PDB 7lmk Chain C

Receptor sequence
>7lmkC (length=156) Species: 9913 (Bos taurus) [Search protein sequence]
NRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYLAR
VTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYI
HSKVQVIYKAPSGAGSATYFYQLWYDQDYARFESPPKTQPTEDNKYKFCA
SCARLA
3D structure
PDB7lmk DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
ChainC
Resolution2.647 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C I763 D765 Y772 W793 F794 E816 E818 D819 Y824 I38 D40 Y47 W68 F69 E91 E93 D94 Y99
BS02 ZN C H790 C817 H65 C92
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:7lmk, PDBe:7lmk, PDBj:7lmk
PDBsum7lmk
PubMed33941775
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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