Structure of PDB 7lg1 Chain C

Receptor sequence
>7lg1C (length=450) Species: 9606 (Homo sapiens) [Search protein sequence]
VVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDY
VSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIP
TDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVM
YIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYW
STLTLTTIGQTPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNA
ARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLK
YLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDY
ICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGS
KAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMK
3D structure
PDB7lg1 Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
ChainC
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG C V526 F544 G545 I547 S548 R561 T562 A563 I565 I602 V371 F389 G390 I392 S393 R406 T407 A408 I410 I447
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7lg1, PDBe:7lg1, PDBj:7lg1
PDBsum7lg1
PubMed33651975
UniProtP29973|CNGA1_HUMAN Cyclic nucleotide-gated channel alpha-1 (Gene Name=CNGA1)

[Back to BioLiP]