Structure of PDB 7lel Chain C

Receptor sequence
>7lelC (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
STVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVK
NPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARM
LQDVFETHFSKIPI
3D structure
PDB7lel Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainC
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMF C W293 F295 V299 L304 N352 W29 F31 V35 L40 N88 BindingDB: Kd=172nM
External links
PDB RCSB:7lel, PDBe:7lel, PDBj:7lel
PDBsum7lel
PubMed34710325
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

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