Structure of PDB 7l99 Chain C

Receptor sequence
>7l99C (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
ASVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNP
MDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQ
DVFETHFSKIPIE
3D structure
PDB7l99 Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XWJ C Y334 R341 M345 Y69 R76 M80
BS02 XWJ C F294 V298 L303 L305 N346 C347 Y350 N351 P352 H355 V357 F29 V33 L38 L40 N81 C82 Y85 N86 P87 H90 V92
BS03 XWJ C Y348 Y350 N351 P352 P353 R362 Y83 Y85 N86 P87 P88 R97
BS04 JEF C M345 K349 P353 M80 K84 P88
External links
PDB RCSB:7l99, PDBe:7l99, PDBj:7l99
PDBsum7l99
PubMed33637650
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

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