Structure of PDB 7l31 Chain C

Receptor sequence
>7l31C (length=339) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMD
YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGAN
FHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLE
SFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKF
TCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGI
TTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV
SRKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRH
3D structure
PDB7l31 Characterization of the subunit composition and structure of adult human glycine receptors
ChainC
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SY9 C F51 F70 R72 L124 R126 F37 F56 R58 L110 R112
BS02 SY9 C Y209 F214 Y195 F200
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0016594 glycine binding
GO:0022824 transmitter-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l31, PDBe:7l31, PDBj:7l31
PDBsum7l31
PubMed
UniProtP23416|GLRA2_HUMAN Glycine receptor subunit alpha-2 (Gene Name=GLRA2)

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