Structure of PDB 7l2t Chain C

Receptor sequence
>7l2tC (length=576) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQ
TALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPL
SLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNT
KFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYI
LQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYS
SSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAA
YYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPS
LKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNM
LYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDG
KYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLL
NMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKL
LQVGFTPDGKDDYRWCFRVDEVNWTT
3D structure
PDB7l2t Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
ChainC
Resolution3.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XJ7 C D509 S510 Y511 S512 E570 K571 Q700 D357 S358 Y359 S360 E418 K419 Q525
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l2t, PDBe:7l2t, PDBj:7l2t
PDBsum7l2t
PubMed34496225
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

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