Structure of PDB 7l2c Chain C

Receptor sequence

>7l2cC (length=222) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKKPGASVKVSCKVSGYTLIELSMHWVRQAPGKGLEWMGG
FDPEDVETIYAQQFQGRVTMTEDTSTDTAYMELSSLRSEDTAVYYCATGW
AYKSTWYFGYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV
KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQ
TYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

7l2c Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.

Chain

Resolution

3.65 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	C	G8 E10	G8 E10
BS02	CA	C	T57 E71	T58 E72

External links

PDB	RCSB:7l2c, PDBe:7l2c, PDBj:7l2c
PDBsum	7l2c
PubMed	33789084

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