Structure of PDB 7l0s Chain C

Receptor sequence
>7l0sC (length=308) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARQSTVDYYLGS
LALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATAL
NVVSLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTM
GLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVASILNT
VIANKLTVMVHQAANMTIEPGRVQALRRGVLVLRAVVIAFVVCWLPYHVR
RLMFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFR
QVFLSTLA
3D structure
PDB7l0s Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
ChainC
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C D54 F128 Y146 V224 R328 F331 I334 D336 W339 F344 Y347 Y351 D3 F70 Y88 V166 R251 F254 I257 D259 W262 F267 Y270 Y274
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7l0s, PDBe:7l0s, PDBj:7l0s
PDBsum7l0s
PubMed33633398
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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