Structure of PDB 7l0p Chain C

Receptor sequence
>7l0pC (length=309) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARLQSTVDYYLG
SLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATA
LNVVSLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFT
MGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVASILN
TVIANKLTVMVHQAANMTIEPGRVQALRRGVLVLRAVVIAFVVCWLPYHV
RRLMFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANF
RQVFLSTLA
3D structure
PDB7l0p Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
ChainC
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C L55 F128 H133 Y146 R327 R328 F331 I334 D336 W339 F344 Y347 L4 F71 H76 Y89 R251 R252 F255 I258 D260 W263 F268 Y271
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l0p, PDBe:7l0p, PDBj:7l0p
PDBsum7l0p
PubMed33633398
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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