Structure of PDB 7krg Chain C

Receptor sequence
>7krgC (length=266) Species: 29918 (Cladosporium herbarum) [Search protein sequence]
PGQQATKHESLLDQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAI
TYASRAQGAEENVKELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQ
IDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTFHCAKAVGHHFKERG
TGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEWRDFARVNS
ISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFASDAST
YTTGADLLIDGGYTTR
3D structure
PDB7krg Biochemical and clinical studies of putative allergens to assess what distinguishes them from other non-allergenic proteins in the same family.
ChainC
Resolution2.03797 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.138: mannitol 2-dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C G27 S29 G33 M34 A54 S55 R56 Q81 V82 N108 A109 G110 T158 S160 Y175 K179 P204 G205 I207 T209 L211 G26 S28 G32 M33 A53 S54 R55 Q80 V81 N107 A108 G109 T157 S159 Y174 K178 P203 G204 I206 T208 L210
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
GO:0050085 mannitol 2-dehydrogenase (NADP+) activity
GO:0050661 NADP binding
GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
Biological Process
GO:0019594 mannitol metabolic process
GO:0051289 protein homotetramerization

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Molecular Function
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Biological Process
External links
PDB RCSB:7krg, PDBe:7krg, PDBj:7krg
PDBsum7krg
PubMed35939227
UniProtP0C0Y5|NMTDH_DAVTA NADP-dependent mannitol dehydrogenase

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