Structure of PDB 7kgy Chain C

Receptor sequence

>7kgyC (length=591) Species: 853 (Faecalibacterium prausnitzii)

NNKSLLYPVVSTSRRVVSLDGMWRFSFDAKSEGVEANWANGLPESISMPV
PASFCDFFTDKESREYCGDFWYETDFFVPGEWSGKDIAIRFGSATHHARI
FVNGVEVAQHEGGFLPFDAVVTDIVRYNQFNKLSVLLNNELNEHMLPAGN
TAVLSNGKKVAAPYFDFYNYAGIHRPVKLMALPTERILDYSVKHRLTAEG
AEVDYTVTTNGDHEVTVELYDGTTKVAEATGKEGTLVVKDAKLWNVHAAY
LYNIVIRIHDGSAVVDEYTEKVGIRTFEIKDGHFLLNGKPVYLRGFGKHE
DADIRGRGLDLATVKRDYELMKWIGANCFRTSHYPYAEELYQMADEEGFL
IIDEVPAVGFMVGWFEKETTPQLLANHKDALTDMIGRDKNHASVIAWSIL
NEPQCTSEGTEAYFKTLFDLAHELDPQKRPRTYAVVMMSLPNNSKGQQFA
DFISLNRYYGWYVMGGMGIVDAEAAFRKEMNGWAQVLNGRPMIFTEYGAD
TMPTEHKLPSVMWSQEYQNEYLDMNHNVFDSYNFVQGELVWNFADFQTTE
GILRVNGNKKGIFTRQRQPKDAAFLFRARWTSLPLDYKGNQ

3D structure

• PDB: 7kgy Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.
• Chain: C
• Resolution: 2.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	I9G	C	D167 H334 E419 Y475 Y479 E513 W558 R571 N575 K577	D166 H333 E402 Y458 Y462 E496 W541 R554 N558 K560

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Nov 25 02:02:32 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7kgy', asym_id = 'C', title = 'Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7kgy', asym_id='C', title='Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004553,0005975', uniprot = '', pdbid = '7kgy', asym_id = 'C'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004553,0005975', uniprot='', pdbid='7kgy', asym_id='C')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>