Structure of PDB 7kc5 Chain C

Receptor sequence
>7kc5C (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIYVI
3D structure
PDB7kc5 Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins
ChainC
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D137 S139 M140 T206 D239 D10 S12 M13 T79 D112
BS02 BJZ C T231 I235 Y257 I259 L302 T104 I108 Y130 I132 L175 BindingDB: IC50=2.5nM
External links
PDB RCSB:7kc5, PDBe:7kc5, PDBj:7kc5
PDBsum7kc5
PubMed
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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