Structure of PDB 7jk4 Chain C

Receptor sequence
>7jk4C (length=612) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MDPTISVSKGCFVYKNGATRSLLGKEVVQQPFYEEYRKAWNQINDHIADL
QHRSYARTLEQLVDFVVGQAEREVLPTAALLTGINQPDHLSQFTALTQRL
HAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVERLRRSQCTMKQL
KSWYTNNFDSERRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVL
GVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAF
HLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSK
ALGRIKQLTHEDMETIRRLPSFRPYVEQICKRIIAVLTDDDYLKKKLPQL
LRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTP
EYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLR
PKLEAIRLAVDEVVKAGRALQKTLQLIETQIVQDHLRALQDAPPIHELFV
FSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLPDL
SVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIKMS
KRKTDHATRLTW
3D structure
PDB7jk4 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
ChainC
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E354 R358 R363 V366 I375 E314 R318 R323 V326 I333
BS02 dna C M658 R711 K712 M563 R602 K603
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jk4, PDBe:7jk4, PDBj:7jk4
PDBsum7jk4
PubMed32848132
UniProtQ7K2L1

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