Structure of PDB 7fh2 Chain C

Receptor sequence
>7fh2C (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTI
KKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQK
INELPT
3D structure
PDB7fh2 A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.
ChainC
Resolution2.492 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4JI C K91 L92 N93 K31 L32 N33
BS02 4JI C W81 Q85 V87 L92 C136 N140 I146 W21 Q25 V27 L32 C76 N80 I86
External links
PDB RCSB:7fh2, PDBe:7fh2, PDBj:7fh2
PDBsum7fh2
PubMed34757034
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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