Structure of PDB 7f75 Chain C

Receptor sequence
>7f75C (length=1133) Species: 1423 (Bacillus subtilis) [Search protein sequence]
VQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPI
EDFTGNLSLEFIDYSLGEPKYPVEESKERDVTYSAPLRVKVRLINKETGE
VKDQDVFMGDFPIMTDTGTFIINGAERVIVSQLVRSPSVYFSGKVDKNGK
KGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQ
EILDLIGENEYLRNTLDKDNTENSDKALLEIYERLRPGEPPTVENAKSLL
DSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDRRTLDKVLP
YLENGIGFRKLYPNGGVVEDEVTLQSIKIFAPTDQEGEQVINVIGNAYIE
EEIKNITPADIISSISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQF
RIGLSRMERVVRERMSIQDTNTITPQQLINIRPVIASIKEFFGSSQLSQF
MDQTNPLAELTHKRRLSALGPGGLTRERAGMEVRDVHYSHYGRMCPIETP
EGPNIGLINSLSSYAKVNRFGFIETPYRRVDPETGKVTGRIDYLTADEED
NYVVAQANARLDDEGAFIDDSIVARFRGENTVVSRNRVDYMDVSPKQVVS
AATACIPFLENDDSNRALMGANMQRQAVPLMQPEAPFVGTGMEYVSGKDS
GAAVICKHGIVERVEAKNVWVRRYEEVDGQKVKGNLDKYSLLKFVRSNQG
TCYNQRPIVSVGDEVVKGEILADGPSMELGELALGRNVMVGFMTWDGYNY
EDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDAL
RNLDDRGIIRIGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKARE
VRDTSLRVPHGGGGIIHDVKVFNREDGDELPPGVNQLVRVYIVQKRKISE
GDKMAGRHGNKGVISKILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQV
LELHMGMAARYLGIHIASPVFDGAREEDVWETLEEAGMSRDAKTVLYDGR
TGEPFDNRVSVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFG
GQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGDNVPE
PGVPESFKVLIKELQSLGMDVKILSGDEEEIEM
3D structure
PDB7f75 Structural basis of transcription activation by the global regulator Spx.
ChainC
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R186 R241 E244 R181 R236 E239
BS02 dna C R452 A456 F470 R1074 M1078 R432 A436 F450 R1053 M1057
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0046677 response to antibiotic
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f75, PDBe:7f75, PDBj:7f75
PDBsum7f75
PubMed34530448
UniProtP37870|RPOB_BACSU DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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